Thursday, 18 February 2016

Testosterone Gel Has Modest Benefits for Men, Study Says

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I hope testosterone gel smeared on their bodies in more than ten million people in recent years who put their young men to know them, and I will increase their libido. But so far, so I do not have any real benefits for healthy testosterone therapy for men with low T. has never been questioned by a strong study

The first results of the research were published Wednesday in the New England Journal of Medicine. The modest benefits, is found in most sexual functioning, but it is a landmark study, the first reliable data on the effects of testosterone on some of its data provider, Dr. Eric S. Orwoll, Oregon Health science and professor of medicine at the University considered the solution.

Some doctors have expressed the hope that he might bring some sanity to the exceptional results testosterone frenzy of recent years. "Frankly," said Dr. Sundeep has a lot of Dan "abuse Khosla, Mayo Clinic College of Medicine." Male student drug tempted by ads, and Dr Khosla said he had heard about the doctors who prescribed without first measuring the person's testosterone levels to see if there were less.

"What I hope is that it will take a more conservative approach," said Dr. Orwoll. "There is a lot of writing, and, for the average person, it does not appear that will have a big impact."

The study, led by University of Pennsylvania Perelman School of Medicine and involved health and AbbVie, funded by the National Institutes of developer testosterone gel AndroGel, the 790 men with low testosterone levels for those ages 65 and older .

Testosterone levels usually fall as men age, but the men were at the lower end - below 275 nanograms per deciliter of blood. Some others of the men said they used to, and they were going to others, much slower than the blah felt as if he had lost his enthusiasm for life, he had lost his sex drive. Men were randomly assigned to use AndroGel or a placebo for one year.

As expected, those who had used the men to end up with significantly higher levels of testosterone AndroGel - 40. The researchers had 19 but wanted to know. What they feel or act differently?

Although men what sex would be like Viagra or Cialis drug is more effective when it came to the penis, sex is in their interest and that the correct conditions report moderate increases in their performance, the researchers reported. Those who reported a small improvement in the mood of feeling blue. But those complaints with drugs or speed walking on the vitality of the men had no discernible effect.

Use heart disease and increases the risk of prostate cancer and other conditions or not: study the short term to solve a long-standing question about small and testosterone gel. And that, Dr. Richard J. Hodes, director of the National Institute on Aging, was intentional.

About 15 years ago, using testosterone gel is worried about the soaring number of men, Dr. Hodes and will go out to thousands of managers, men in the Department of Veterans Affairs a large clinical trial were presented suggesting that the risks and benefits of testosterone therapy. But the plan ran into resistance.

Participants were real dangers for men, critics said. Ofcancer and not just risk, emerged after the possibility of heart disease, but P.S.A. With a test used to screen for prostate cancer blood test. Testosterone P.S.A. Increases levels. Men with higher levels typically obtained for biopsy to look for cancer in their prostates. In a large clinical trial, investigators are not drugs and those who know who is getting a placebo. The men taking testosterone thousands P.S.A. From fully levels can result from cancer ended with biopsy, were raised by drugs.

The doctor turned to the Institute of Medicine to guide Hodes. A group of medical experts recommend starting small. He said, a study is of no use in older healthy men with low testosterone hormone levels if asked before. If no benefit, why a trial?

The result of new research. The study is used by men in the testosterone gel is injected to bodybuilders and athletes to enhance muscle growth and performance that are not as powerful as testosterone and as much higher doses of hormones.

The use of free testosterone in the body as a male hormone therapy with serious medical conditions and it is not practical question, researchers said. The men who have been large increases testosterone levels because they just dropped.

David Bostick, the appeal of a 71-year-old Pittsburgh man who participated in the study, was that testosterone may help them feel sluggish and low libido. Smearing a gel after a few weeks of us - it was not known if it was a AndroGel or placebo - on her stomach, with more sexual desire and energy, started to feel different. The measure must be received testosterone. At the end of the study saw their primary care physician and get a prescription for AndroGel. He knew that there were risks, but he made a conscious decision to take him on Saturday. "" He was in jail he had used, he received a letter telling him to study. It was testosterone.

But remains concerned about the risks. Last summer, the Food and Drug Administration asked manufacturers of a large clinical trial process of testosterone gel that is announced to evaluate whether the risk of heart drugs. Companies are working on the design, it's Morry Smulevitz, a spokesman for AbbVie.

For now, doctors are divided on whether the emphasis on the study results. Dr. William Bremner, professor of medicine at the University of Washington, said now the solid, if equipped with short-term data, they can treat low testosterone levels show that men are saying, "I think there is a reasonable thing to do about. "

Dr. Joel Finkelstein, a professor of medicine at Harvard, was less sanguine than that. "Testosterone is clearly not a panacea," he said. He is concerned about the long-term risks and the number of times men inspired concern about the lack of data on induced to take a drug without knowing. For now, that they can respond to escape from the large number of men exposed to potential dangers like to know more about it.

But large clinical trial that P.S.A. Even if it means dealing with go ahead, to the problem.

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